When the Santé Fe Railroad built its line in 1881, the station was placed on the Texas side and named La Tuna, which is Spanish for "prickly pear cactus". A Spanish-speaking woman named Sabrina, who had a chapel on the New Mexico side which was dedicated to Saint Anthony of Padua, insisted on the name Anthony rather than La Tuna for the new town.
Source: Tarpley, Fred (5 July 2010). 1001 Texas Place Names. University of Texas Press. p. 11. ISBN 978-0-292-78693-6.
La Tuna Correctional Facility opened.
The first post office opened. It closed in 1965.
The estimated population was 20 people.
The Town of Anthony was incorporated.
Ernie Rascon, a local police officer, was killed in the line of duty.
Leap Year Capital of the World. Started by Mary Brown to honor leap year babies in Anthony, including her neighbor and friend Bettie Luis.